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When you think about book printing, you probably don't think about the paper's grain you will be printing on, but your printer should. If they print using the wrong paper grain, it can eventually sabotage your book. The paper grain should to run parallel to the book's binding edge so the pages will open naturally. If the grain goes the other way, (against the bind), the book will stay open. Readers will have to crack the spine or lay the book flat to keep it from snapping shut. This will eventually break the spine, and then the pages can loosen and get lost.
*If your book printer doesn't know what paper grain is, you should look for another, more knowledgeable printer.